Following is the list of Top 10 Most Profitable Movies Of All Time:
| S.No. | Movie | Return on Investment | Budget | Gross Revenue |
| 1 | My Big Fat Greek Wedding (2002) | 6150% | $6 million (inflation adjusted) | $369 million |
| 2 | E.T. the Extra-Terrestrial (1982) | 3172% | $25 million (inflation adjusted) | $793 million |
| 3 | Slumdog Millionaire (2008) | 2520% | $15 million (inflation adjusted) | $378 million |
| 4 | Pretty Woman (1990) | 2013% | $23 million(inflation adjusted) |
$463
million
|
| 5 | Grease (1978) | 1975% | $20 million (inflation adjusted) | $394 million |
| 6 | Star Wars (1977) | 1938% | $40 million (inflation adjusted) | $775 million |
| 7 | American Beauty (1999) | 1780% | $20 million (inflation adjusted) | $356 million |
| 8 | The Passion of the Christ (2004) | 1749% | $35 million (inflation adjusted) | $612 million |
| 9 | Home Alone (1990) | 1590% | $30 million (inflation adjusted) | $477 million |
| 10 | Ghost (1990) | 1446% | $35 million (inflation adjusted) | $506 million |
